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Researchers 3D print cacao-based health supplement

The study from Queen’s University Belfast combines the nutritional benefits of Greek honey with Vitamin D3

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According to Queen’s University Belfast, researchers have developed a first-of-its-kind 3D printed cacao-based health supplement that acts as a nutrient and vitamin carrier – helping to boost the immune system. This new 3D printed formulation combines the nutritional benefits of Greek honey with Vitamin D3 – both of which are known for their role in supporting the immune system.

This Greek honey contains thyme and asfaka (Greek sage), which both possess strong antimicrobial and antioxidant properties. Thyme strengthens the immune system, providing a particular anti-inflammatory effect, especially in respiratory infections. Asfaka contains phenolic compounds that protect against oxidative stress and microbial infections, while it helps to treat inflammatory diseases, such as arthritis.

The use of 3D printing technology for these novel supplements is a more sustainable approach to producing personalized nutrient formulations compared to conventional manufacturing methods.

The study was led by Professor Dimitrios Lamprou from the School of Pharmacy at Queen’s University Belfast alongside a team of researchers including; PhD Students, Rachel Milliken, Aikaterini Dedeloudi, and Robyn Irwin; BSc Undergraduate Student, Emily Vong; Dr Sune Andersen, Industrial Collaborator; and Dr Matthew Wylie, Lecturer.

Queen’s University Belfast researchers 3D print a cacao-based health supplement that combines the benefits of Greek honey with Vitamin D3.

“Greek honey has a complex chemical composition that makes it a valuable nutritional ingredient for good health. This study has shown that the honey investigated has multiple beneficial properties, making them valuable both for improving health and for preventing and treating various diseases,” said Professor Dimitrios Lamprou. “Incorporating honey into 3D printed cacao-based dosage forms, palatability, and patient compliance can be improved, and personalized health supplements and nutraceuticals can be easily prepared.”

“With my previous background as a pharmacist, I know all too well the potential issues poor patient adherence to medications can have on treatment efficacy. This is especially the case for younger patients who may refuse to take medications due to poor palatability,” said Dr. Matthew Wylie, Lecturer from the School of Pharmacy at Queen’s University Belfast. “Our approach provides a simple way to potentially improve the acceptability of medicines through the taste-masking properties of cacao and honey. Moreover, we have shown the Greek honey variants used in this study possessed inhibitory effects against pathogenic bacteria which could provide further health benefits.”

The project received funding for Emily Vong’s summer project through the School of Pharmacy at Queen’s University Belfast, and the honey was provided by the beekeeper Ioannis Argyris from Euboea Island in Greece.

The research has been published in Current Research in Food Science.

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